학술논문

Quantification of human bocavirus in lower respiratory tract infections in China
Document Type
article
Source
Infectious Agents and Cancer, Vol 2, Iss 1, p 3 (2007)
Subject
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1750-9378
Abstract
Abstract A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 × 103 to 8.0 × 109 in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fever and cough. Our results suggest that HBoV may be an important etiological agent of LRTI in children in China.