학술논문

Vitreous and Optic Nerve Infiltration of an Adrenal B Lymphoma
Document Type
article
Source
Case Reports in Ophthalmology, Vol 12, Iss 3, Pp 915-920 (2021)
Subject
lymphoma
metastases
vitritis
optic disc edema
methotrexate
Ophthalmology
RE1-994
Language
English
ISSN
1663-2699
Abstract
Aim: This study aimed to report a case of vitreous and optic nerve infiltration of a primary adrenal B lymphoma. Case Report: An 81-year-old patient consulted for decrease in vision in the left eye and pain with ocular movements during the last week. The patient was being treated with chemotherapy for an adrenal gland diffuse large B-cell lymphoma. On examination, vitritis was seen in both eyes and optic disc edema in his left eye. After an extensive study based on orbital and brain magnetic resonance imaging and vitreous cytology, an ocular infiltration by systemic B lymphoma was confirmed. A treatment based on intravitreal methotrexate was carried out, achieving the regression of the vitreous infiltration and resolution of the optic disc edema. Systemic B lymphoma metastasizing ocular structures is extremely infrequent. The manifestations may mimic an inflammatory disease. Ophthalmologists should be aware of these manifestations and consider among the masquerade syndromes.