학술논문
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals
Document Type
article
Author
Pei Xue; Ilona Merikanto; Frances Chung; Charles M. Morin; Colin Espie; Bjørn Bjorvatn; Jonathan Cedernaes; Anne-Marie Landtblom; Thomas Penzel; Luigi De Gennaro; Brigitte Holzinger; Kentaro Matsui; Harald Hrubos-Strøm; Maria Korman; Damien Leger; Sérgio Mota-Rolim; Courtney J. Bolstad; Michael Nadorff; Giuseppe Plazzi; Catia Reis; Rachel Ngan Yin Chan; Yun Kwok Wing; Juliana Yordanova; Adrijana Koscec Bjelajac; Yuichi Inoue; Markku Partinen; Yves Dauvilliers; Christian Benedict
Source
Translational Psychiatry, Vol 13, Iss 1, Pp 1-7 (2023)
Subject
Language
English
ISSN
2158-3188
Abstract
Abstract Short nighttime sleep duration impairs the immune response to virus vaccination, and long nighttime sleep duration is associated with poor health status. Thus, we hypothesized that short (9 h) nighttime sleepers have a higher post-COVID risk than normal nighttime sleepers, despite two doses of mRNA vaccine (which has previously been linked to lower odds of long-lasting COVID-19 symptoms). Post-COVID was defined as experiencing at least one core COVID-19 symptom for at least three months (e.g., shortness of breath). Multivariate logistic regression adjusting for age, sex, BMI, and other factors showed in 9717 respondents (age span 18–99) that two mRNA vaccinations lowered the risk of suffering from post-COVID by about 21% (p