학술논문
Approaches to Establishing Tolerance in Immune Mediated Diseases
Document Type
article
Author
Source
Frontiers in Immunology, Vol 12 (2021)
Subject
Language
English
ISSN
1664-3224
Abstract
The development of rational approaches to restore immune tolerance requires an iterative approach that builds on past success and utilizes new mechanistic insights into immune-mediated pathologies. This article will review concepts that have evolved from the clinical trial experience of the Immune Tolerance Network, with an emphasis on lessons learned from the innovative mechanistic studies conducted for these trials and new strategies under development for induction of tolerance.