학술논문
Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
Document Type
article
Author
Carolina Moretto Carnielli; Carolina Carneiro Soares Macedo; Tatiane De Rossi; Daniela Campos Granato; César Rivera; Romênia Ramos Domingues; Bianca Alves Pauletti; Sami Yokoo; Henry Heberle; Ariane Fidelis Busso-Lopes; Nilva Karla Cervigne; Iris Sawazaki-Calone; Gabriela Vaz Meirelles; Fábio Albuquerque Marchi; Guilherme Pimentel Telles; Rosane Minghim; Ana Carolina Prado Ribeiro; Thaís Bianca Brandão; Gilberto de Castro; Wilfredo Alejandro González-Arriagada; Alexandre Gomes; Fabio Penteado; Alan Roger Santos-Silva; Márcio Ajudarte Lopes; Priscila Campioni Rodrigues; Elias Sundquist; Tuula Salo; Sabrina Daniela da Silva; Moulay A. Alaoui-Jamali; Edgard Graner; Jay W. Fox; Ricardo Della Coletta; Adriana Franco Paes Leme
Source
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
Oral cancer has region-specific histopathological and molecular characteristics, complicating its classification by the standard tumor-node-metastasis system. Here, the authors combine discovery and targeted proteomics with IHC to identify region-specific and saliva biomarkers for oral cancer prognosis.