학술논문

Significance of prediabetes as a nosological entity
Document Type
article
Source
Biomedical Papers, Vol 162, Iss 4, Pp 249-257 (2018)
Subject
prediabetes
impaired fasting glucose
impaired glucose tolerance
prevalence
cardiovascular complications
cancer
Medicine
Language
English
ISSN
1213-8118
1804-7521
Abstract
Prediabetes is a glucose metabolism disorder considered as a distinct nosological entity which strongly predicts the development of type 2 diabetes mellitus. This nosological entity itself is a serious condition indicating an increased risk of atherosclerotic and oncological complications. In patients with prediabetes, other components of metabolic syndrome are usually present, such as arterial hypertension, obesity or dyslipidaemia, further increasing an individual's risk of morbidity and mortality. Prediabetes is a long-developing disorder which offers enough time for early diagnosis and intervention; it may even be reversible. This review summarizes current knowledge on the definition, detection, epidemiology, cardiovascular and other consequences of prediabetes. It also gives suggestions for future research, along with recommendations for clinical practice.