학술논문
原发性干燥综合征炎症发病机制 / Inflammatory pathogenesis of Primary Sj?gren's syndrome
Document Type
Academic Journal
Source
中国免疫学杂志 / Chinese Journal of Immunology. 39(12):2679-封3
Subject
Language
Chinese
ISSN
1000-484X
Abstract
原发性干燥综合征(pSS)是累及多种外分泌腺为主的慢性炎症性自身免疫病,是风湿病科一大类常见的自身免疫病,但是pSS的发病机制仍不明确,以致治疗手段不足.而国际上对于pSS的研究也在日益增多,回顾关于干燥综合征在不同因素下的机制的文献,本文从遗传、环境、自身免疫细胞及自身抗体等因素对干燥综合征的发病机制总结.
Primary Sj?gren's syndrome(pSS)is a chronic inflammatory autoimmune disease involving a variety of exocrine glands.It is a common autoimmune disease in the department of rheumatology.However,the pathogenesis of pSS is still unclear,re-sulting in lack of treatment.While the international research on pSS is also increasing,we review the latest literature on the mecha-nism of Sj?gren's syndrome under different factors.In this paper,the process mechanism of Sj?gren's syndrome is summarized from the aspects of heredity,environment,autoimmune cells and autoantibodies.
Primary Sj?gren's syndrome(pSS)is a chronic inflammatory autoimmune disease involving a variety of exocrine glands.It is a common autoimmune disease in the department of rheumatology.However,the pathogenesis of pSS is still unclear,re-sulting in lack of treatment.While the international research on pSS is also increasing,we review the latest literature on the mecha-nism of Sj?gren's syndrome under different factors.In this paper,the process mechanism of Sj?gren's syndrome is summarized from the aspects of heredity,environment,autoimmune cells and autoantibodies.