학술논문
Kinetics of isotope exchange between [3-(iodophenyl)methyl]guanidine (mIBG) and [131 I]-iodide
Document Type
Article
Author
Source
Journal of Radioanalytical and Nuclear Chemistry; April 1992, Vol. 158 Issue: 1 p183-191, 9p
Subject
Language
ISSN
02365731; 15882780
Abstract
Abstract: The reaction of isotope exchange between [3-(iodophenyl)methyl]guanidine, mIBG, and [131 ]-iodide in relatively concentrated solutions, in the presence of different ammonium salts, in a closed system, over the temperature range from 130 to 150°C, has been investigated. The reaction occurs either with (NH4 )2 SO4 or CH3 COOH, which indicates that the reaction goes through some intermediate stages. Kinetic studies show the influence of the additives. The activation energies for the reaction with (NH4 )2 SO4 /H2 O, (NH4 )2 SO4 /CH3 COOH and CH3 COOH are 121.1, 115.1 and 84.5 kJ·mol–1 , respectively.