학술논문
Prevalence and Risk of Down Syndrome in Monozygotic and Dizygotic Multiple Pregnancies in Europe
Document Type
Article
Author
Source
Obstetrical and Gynecological Survey; October 2014, Vol. 69 Issue: 10 p583-585, 3p
Subject
Language
ISSN
00297828; 15339866
Abstract
During the past 20 years, the prevalence of Down syndrome (DS) has increased with the increase in mean maternal age. The prevalence of multiple births has also increased because of older maternal age and use of assisted reproductive technologies. This study was designed to determine the maternal age–specific prevalence of DS in monozygotic and dizygotic pregnancies, assess risk relative to singleton pregnancies, as well as compare prenatal diagnosis and pregnancy outcomes for DS fetuses in multiple and singleton pregnancies.