학술논문
Mesenchymal stem cell transplantation in a premature infant with octreotide induced fulminant necrotizing enterocolitis
Document Type
Article
Source
Journal of Neonatal Nursing; April 2022, Vol. 28 Issue: 2 p130-133, 4p
Subject
Language
ISSN
13551841
Abstract
Necrotizing enterocolitis (NEC) continues to cause significant morbidity and mortality in the newborn period. The mortality rate among severe NEC patients requiring surgery is over 50 %. The capacity of mesenchymal stem cells (MSC) for self-replication, differentiation, preventing apoptosis, and reducing inflammation has caused an interest for their use in NEC therapy. Here we present an infant treated with human umbilical cord-derived MSC transplantation 30 days after undergoing surgery for extensive fulminant NEC.