학술논문

Double-Blind Evaluation of Nimesulide vsLysine-Aspirin in the Treatment of Paediatric Acute Respiratory Tract Infections
Document Type
Article
Source
Drugs; November 1993, Vol. 46 Issue: Supplement 1 p219-221, 3p
Subject
Language
ISSN
00126667
Abstract
70 children aged 4 to 12 years with acute infection and inflammation of the respiratory tract (laryngitis, tracheitis, bronchitis, pneumonia) were enrolled in a double-blind investigation and randomised to treatment with nimesulide (50mg granules twice daily) or lysine-aspirin (360mg granules twice daily) for 5 days. The drugs were similarly effective in reducing cough, asthenia and dyspnoea, although nimesulide-treated patients experienced fewer gastrointestinal adverse events. These results confirm the efficacy of nimesulide in the treatment of respiratory inflammation and provide preliminary evidence of its value in children.