학술논문
Stronger effect of amyloid load than APOEgenotype on cognitive decline in healthy older adults
Document Type
Article
Author
Lim, Yen Ying; Ellis, Kathryn A.; Pietrzak, Robert H.; Ames, David; Darby, David; Harrington, Karra; Martins, Ralph N.; Masters, Colin L.; Rowe, Christopher; Savage, Greg; Szoeke, Cassandra; Villemagne, Victor L.; Maruff, Paul; Rembach, Alan; Bahar-Fuchs, Alex; Milner, Andrew; Bush, Ashley; Brown, Belinda; Wilson, Bill; Trounson, Brett; O'Halloran, Christopher; Trivedi, Darshan; Lamb, Fiona; Chetelat, Gael; Jones, Gareth; O'Keefe, Graeme; Lui, James; Robertson, Jo; Fripp, Jurgen; Pertile, Kelly; Farrow, Maree; Woodward, Michael; Rimajova, Miroslava; Killeen, Neil; Lautenschlager, Nicola; Faux, Noel; Yastrubetskaya, Olga; Salvado, Olivier; Raniga, Parnesh; Yates, Paul; Bourgeat, Pierrick; Li, Qiao-Xin; Lachovitski, Rebecca; Rumble, Rebecca; Clarnette, Roger; Laws, Simon; McBride, Simon; Taddei, Tania; Cowie, Tiffany; Ward, Vanessa; Dore, Vincent
Source
Neurology (Ovid); October 2012, Vol. 79 Issue: 16 p1645-1652, 8p
Subject
Language
ISSN
00283878; 1526632X
Abstract
Although the APOE4allele is associated with more rapid decline in memory in healthy older adults, the significance of elevated cerebral -amyloid (A) load for longitudinal changes in cognition is unclear.