학술논문
Immunological and virological findings in a patient with exceptional post-treatment control: a case report
Document Type
Article
Author
Climent, Núria; Ambrosioni, Juan; González, Tània; Xufré, Cristina; Casadellà, Maria; Noguera-Julian, Marc; Paredes, Roger; Plana, Montserrat; Grau-Expósito, Judith; Mallolas, Josep; Alcamí, José; Sánchez-Palomino, Sonsoles; Miró, José M; Nicolás, David; Xufré, Cristina; Hurtado, Carmen; Rovira, Cristina; Sued, Omar; Brunet, Mercé; López-Diéguez, María; Manzardo, Christian; Agüero, Fernando; Tuset, Montserrat; Guardo, Alberto C; Marcos, Maria A.; del Mar Mosquera, María; Muñoz-Fernández, M. Ángeles; Caballero, Miguel; Ligero, Carmen; Fernández, Emma; Marcos, M. Ángeles; Gatell, José M; de Lazzari, Elisa; Gallart, Teresa; Fernandez-Tenreiro, Ana; Gomez, Begoña; Berrocal, Leire; Nicolás, David; Xufré, Cristina; Hurtado, Carmen; Rovira, Cristina; Sued, Omar; Brunet, Mercé; López-Diéguez, María; Manzardo, Christian; Agüero, Fernando; Tuset, Montserrat; Guardo, Alberto C; Marcos, Maria A.; Mosquera, María del Mar; Muñoz-Fernández, M. Ángeles; Caballero, Miguel; Ligero, Carmen; Fernández, Emma; Marcos, M. Ángeles; Gatell, José M; de Lazzari, Elisa; Gallart, Teresa; Fernandez-Tenreiro, Ana; Gomez, Begoña; Berrocal, Leire
Source
The Lancet HIV; January 2023, Vol. 10 Issue: 1 pe42-e51, 10p
Subject
Language
ISSN
24054704; 23523018
Abstract
Although antiretroviral therapy (ART) is effective in suppressing viral replication, HIV-1 persists in reservoirs and rebounds after ART has been stopped. However, a very few people (eg, elite and post-treatment controllers) are able to maintain viral loads below detection limits without ART, constituting a realistic model for long-term HIV remission. Here, we describe the HIV control mechanisms of an individual who showed exceptional post-treatment control for longer than 15 years.