학술논문
Haemodynamic effects of valsartan in acute renal ischaemia/reperfusion injury.
Document Type
Article
Author
Source
Nephrology Dialysis Transplantation; August 2001, Vol. 16 Issue: 8 p1592-1597, 6p
Subject
Language
ISSN
09310509; 14602385
Abstract
Acute deterioration of renal function is an important side-effect of angiotensin-converting enzyme (ACE) inhibitors, especially if accompanied by other nephrotoxic events. Angiotensin II receptor(1) blockers (ARB) are thought to have fewer side-effects on renal perfusion and function. We examined the effects of valsartan (VAL) on kidney function as well as the contribution of the nitric oxide (NO) system in a rat model of ischaemic acute renal failure (ARF).