학술논문
The curious case of type I IFN and MxA: tipping the immune balance in AIDS.
Document Type
Article
Source
Frontiers in Immunology; Sep2014, Vol. 5, p1-4, 4p
Subject
Language
ISSN
16643224
Abstract
The article discusses research on type I interferon (IFNI) and myxovirus resistance protein (MxA) gene in immune activation in relation to acquired immunodeficiency syndrome (AIDS). Topics discussed include the function of plasmacytoid dendritic cells (pDC) to produce IFN in response to bacterial and viral DNA, production of IFNI, and exertion of the antiviral activity of Mx proteins.