학술논문
The potential of 3T high-resolution magnetic resonance imaging for diagnosis, staging, and follow-up of retinoblastoma.
Document Type
Academic Journal
Author
de Jong MC; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: mc.dejong@vumc.nl.; de Graaf P; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands.; Brisse HJ; Department of Radiology, Institut Curie, Paris, France.; Galluzzi P; Unit of Diagnostic and Therapeutic Neuroradiology, Department of Neurosciences, Azienda Ospedaliera Universitaria Senese, Siena, Italy.; Göricke SL; Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Germany.; Moll AC; Department of Ophthalmology, VU University Medical Center, Amsterdam, The Netherlands.; Munier FL; Jules-Gonin Eye Hospital, Lausanne, Switzerland.; Popovic MB; Pediatric Hematology-Oncology Unit, University Hospital, Lausanne, Switzerland.; Moulin AP; Pathology Unit, Jules-Gonin Eye Hospital, Lausanne, Switzerland.; Binaghi S; Department of Radiology, University Hospital, Lausanne, Switzerland.; Castelijns JA; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands.; Maeder P; Department of Radiology, University Hospital, Lausanne, Switzerland.
Source
Publisher: Elsevier Science Country of Publication: United States NLM ID: 0404551 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3304 (Electronic) Linking ISSN: 00396257 NLM ISO Abbreviation: Surv Ophthalmol Subsets: MEDLINE
Subject
Language
English
Abstract
We demonstrate the value of high-resolution magnetic resonance imaging (MRI) in diagnosing, staging, and follow-up of retinoblastoma during eye-saving treatment. We have included informative retinoblastoma cases scanned on a 3T MRI system from a retrospective retinoblastoma cohort from 2009 through 2013. We show that high-resolution MRI has the potential to detect small intraocular seeds, hemorrhage, and metastatic risk factors not visible with fundoscopy (e.g., optic nerve invasion and choroidal invasion), and treatment response. Unfortunately, however, the diagnostic accuracy of high-resolution MRI is not perfect, especially for subtle intraocular seeds or minimal postlaminar optic nerve invasion. The most important application of MRI is the detection of metastatic risk factors, as these cannot be found by fundoscopy and ultrasound.
(Copyright © 2015 Elsevier Inc. All rights reserved.)
(Copyright © 2015 Elsevier Inc. All rights reserved.)