학술논문
Antimicrobial Resistance in a Tertiary Care Hospital in Armenia: 2016-2019.
Document Type
Academic Journal
Author
Davtyan H; Tuberculosis Research and Prevention Center NGO, Yerevan 0014, Armenia.; Grigoryan R; Tuberculosis Research and Prevention Center NGO, Yerevan 0014, Armenia.; Niazyan L; Nork Infection Clinical Hospital of Ministry of Health of Armenia, Yerevan 0047, Armenia.; Davidyants M; Nork Infection Clinical Hospital of Ministry of Health of Armenia, Yerevan 0047, Armenia.; Ghalechyan T; Nork Infection Clinical Hospital of Ministry of Health of Armenia, Yerevan 0047, Armenia.; Davtyan K; Tuberculosis Research and Prevention Center NGO, Yerevan 0014, Armenia.
Source
Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101709042 Publication Model: Electronic Cited Medium: Internet ISSN: 2414-6366 (Electronic) Linking ISSN: 24146366 NLM ISO Abbreviation: Trop Med Infect Dis Subsets: PubMed not MEDLINE
Subject
Language
English
Abstract
Antimicrobial resistance (AMR) is the acquired ability of pathogens to withstand antimicrobial treatment. To bridge the gap in knowledge for implementing effective and targeted interventions in relation to the AMR in Armenia, we designed this study to explore the performance of AMR diagnostics and the profile of AMR in the Nork Infection Clinical Hospital (NICH) for the period of 2016-2019, particularly to (i) determine the proportions of antimicrobial resistance among all samples tested at the hospital laboratory, (ii) determine the proportion of resistance against specific antimicrobials, and (iii) identify factors associated with AMR. A cross-sectional study was conducted with a secondary data analysis that included all the patients tested for AMR in the laboratory of the NICH for the period of 2016-2019. For this period, only 107 (0.3%) patients out of 36,528 had their AMR test results available and of them, 87 (81%) had resistance at least to one tested antimicrobial. This study has provided some valuable information on the AMR situation in Armenia. The results call for immediate actions to control the access to and the use of antimicrobials, strengthen AMR surveillance, and improve laboratory capacity for the proper and fast identification of drug resistance through a comprehensive system.