학술논문
Efficacy of a Digital Health Preventive Intervention for Adolescents With HIV or Sexually Transmitted Infections and Substance Use Disorder: Protocol for a Randomized Controlled Trial.
Document Type
Academic Journal
Author
Cordova D; School of Social Work, University of Michigan, Ann Arbor, MI, United States.; Bauermeister JA; School of Nursing, University of Pennsylvania, Philadelphia, PA, United States.; Warner S; School of Public Health, University of Michigan, Ann Arbor, MI, United States.; Wells P; The Corner Health Center, Ypsilanti, MI, United States.; MacLeod J; Livingston Physician Organization, Livingston, MI, United States.; Neilands TB; School of Medicine, University of California San Francisco, San Francisco, CA, United States.; Mendoza Lua F; Crown Family School of Social Work, Policy, and Practice, University of Chicago, Chicago, IL, United States.; Delva J; School of Social Work, Boston University, Boston, MA, United States.; Fessler KB; The Corner Health Center, Ypsilanti, MI, United States.; Smith V Jr; Khreizat S; School of Social Work, University of Michigan, Ann Arbor, MI, United States.; Boyer C; School of Medicine, University of California San Francisco, San Francisco, CA, United States.
Source
Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101599504 Publication Model: Electronic Cited Medium: Print ISSN: 1929-0748 (Print) Linking ISSN: 19290748 NLM ISO Abbreviation: JMIR Res Protoc Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
1929-0748
Abstract
Background: HIV or sexually transmitted infections remain a significant public health concern in the United States, with adolescents affected disproportionately. Adolescents engage in HIV/STI risk behaviors, including drug use and condomless sex, which increase the risk for HIV/STIs. At-risk adolescents, many of whom are racial minorities, experience HIV/STI disparities. Although at-risk adolescents are disproportionately affected by HIV/STI risk behaviors and infections and although the Centers for Disease Control and Prevention recommends routine HIV/STI testing for adolescents, relatively few adolescents report having ever been tested for HIV/STI. With expected increases in health clinic visits as a result of the Affordable Care Act combined with technological advances, health clinics and mobile health (mHealth), including apps, provide innovative contexts and tools to engage at-risk adolescents in HIV/STI prevention programs. Yet, there is a dearth of efficacious mHealth interventions in health clinics to prevent and reduce both condomless sex and drug use and increase HIV/STI testing for at-risk adolescents.
Objective: To address this gap in knowledge, we developed a theory-driven, culturally congruent mHealth intervention (hereon referred to as S4E [Storytelling 4 Empowerment]) that has demonstrated feasibility and acceptability in a clinical setting. The next step is to examine the preliminary efficacy of S4E on adolescent HIV/STI testing and risk behaviors. This goal will be accomplished by 2 aims: the first aim is to develop a cross-platform and universal version of S4E. The cross-platform and universal version of S4E will be compatible with both iOS and Android operating systems and multiple mobile devices, aimed at providing adolescents with ongoing access to the intervention once they leave the clinic, and the second aim is to evaluate the preliminary efficacy of S4E, relative to usual care control condition, in preventing or reducing drug use and condomless sex and increasing HIV/STI testing in a clinical sample of at-risk adolescents aged 14-21 years living in Southeast Michigan.
Methods: In this study, 100 adolescents recruited from a youth-centered community health clinic will be randomized via blocked randomization with random sequences of block sizes to one of the 2 conditions: S4E mHealth intervention or usual care. Theory-driven and culturally congruent, S4E is an mHealth adaptation of face-to-face storytelling for empowerment, which is registered with the Substance Abuse and Mental Health Services Administration's National Registry of Evidence-Based Programs and Practices.
Results: This paper describes the protocol of our study. The recruitment began on May 1, 2018. This study was registered on December 11, 2017, in ClinicalTrials.gov. All participants have been recruited. Data analysis will be complete by the end of March 2024, with study findings available by December 2024.
Conclusions: This study has the potential to improve public health by preventing HIV/STI and substance use disorders.
Trial Registration: ClinicalTrials.gov NCT03368456; https://clinicaltrials.gov/study/NCT03368456.
International Registered Report Identifier (irrid): DERR1-10.2196/47216.
(©David Cordova, José A Bauermeister, Sydni Warner, The Youth Leadership Council, Patricia Wells, Jennifer MacLeod, Torsten B Neilands, Frania Mendoza Lua, Jorge Delva, Kathryn Bondy Fessler, Versell Smith Jr, Sarah Khreizat, Cherrie Boyer. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 19.02.2024.)
Objective: To address this gap in knowledge, we developed a theory-driven, culturally congruent mHealth intervention (hereon referred to as S4E [Storytelling 4 Empowerment]) that has demonstrated feasibility and acceptability in a clinical setting. The next step is to examine the preliminary efficacy of S4E on adolescent HIV/STI testing and risk behaviors. This goal will be accomplished by 2 aims: the first aim is to develop a cross-platform and universal version of S4E. The cross-platform and universal version of S4E will be compatible with both iOS and Android operating systems and multiple mobile devices, aimed at providing adolescents with ongoing access to the intervention once they leave the clinic, and the second aim is to evaluate the preliminary efficacy of S4E, relative to usual care control condition, in preventing or reducing drug use and condomless sex and increasing HIV/STI testing in a clinical sample of at-risk adolescents aged 14-21 years living in Southeast Michigan.
Methods: In this study, 100 adolescents recruited from a youth-centered community health clinic will be randomized via blocked randomization with random sequences of block sizes to one of the 2 conditions: S4E mHealth intervention or usual care. Theory-driven and culturally congruent, S4E is an mHealth adaptation of face-to-face storytelling for empowerment, which is registered with the Substance Abuse and Mental Health Services Administration's National Registry of Evidence-Based Programs and Practices.
Results: This paper describes the protocol of our study. The recruitment began on May 1, 2018. This study was registered on December 11, 2017, in ClinicalTrials.gov. All participants have been recruited. Data analysis will be complete by the end of March 2024, with study findings available by December 2024.
Conclusions: This study has the potential to improve public health by preventing HIV/STI and substance use disorders.
Trial Registration: ClinicalTrials.gov NCT03368456; https://clinicaltrials.gov/study/NCT03368456.
International Registered Report Identifier (irrid): DERR1-10.2196/47216.
(©David Cordova, José A Bauermeister, Sydni Warner, The Youth Leadership Council, Patricia Wells, Jennifer MacLeod, Torsten B Neilands, Frania Mendoza Lua, Jorge Delva, Kathryn Bondy Fessler, Versell Smith Jr, Sarah Khreizat, Cherrie Boyer. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 19.02.2024.)