부산대학교 도서관

Alopecia areata (AA) is an immune-mediated inflammatory disorder that targets anagen phase hair follicles (HFs), leading to nonscarring hair loss.[1] Several autoimmune diseases are commonly associated with AA. Herein we describe two cases (Table) of patients affected by AA, who have developed after several years multiple sclerosis (MS), which is one of the most frequent autoimmune diseases of the central nervous system. Tada I et al. i [3] conducted a study on 70 patients with MS and found that five patients (Male/Female = 4/1) were complicated with AA. Interestingly, AA has been recently hypothesized as a possible side effect of anti-CD52 monoclonal antibody alemtuzumab, which is used for treatment of relapsing-remitting MS.[[5], [7]] In fact, AA had been reported during alemtuzumab therapy in five patients. [Extracted from the article]