학술논문
Photochirogenesis with mutant human serum albumins: enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate.
Document Type
Article
Author
Source
Subject
*SERUM albumin
*CARBOXYLATES
*CHIRALITY
*BLOOD proteins
*ANIONS
*
*
*
*
Language
ISSN
1359-7345
Abstract
Mutant human serum albumins accelerated the photocyclodimerization of 2-anthracenecarboxylate to afford chiral cyclodimers in 75–85% enantiomeric excesses, revealing that the mutations to impair non-productive sites 1 and/or 2 enhanced the substrate binding to site 3 without seriously damaging its inherently high photochirogenic ability. [ABSTRACT FROM AUTHOR]