학술논문
Bordetella pertussis Strain Lacking Pertactin and Pertussis Toxin.
Document Type
Journal Article
Author
Source
Subject
*BORDETELLA pertussis
*PERTUSSIS toxin
*VACCINATION of infants
*DELETION mutation
*GENOMES
*WHOOPING cough
*BACTERIAL toxins
*MEMBRANE proteins
*GENETIC mutation
*WHOOPING cough vaccines
*PREVENTION
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Language
ISSN
1080-6040
Abstract
A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an unvaccinated infant in New York State in 2013. Comparison with a French strain that was pertussis toxin-deficient, pertactin wild-type showed that the strains carry the same 28-kb deletion in similar genomes. [ABSTRACT FROM AUTHOR]