학술논문
Antibiotic exposure and resistance development in Pseudomonas aeruginosa and Enterobacter species in intensive care units.
Document Type
Article
Author
Source
Subject
*DRUG resistance in microorganisms
*PSEUDOMONAS aeruginosa
*ENTEROBACTER
*CRITICAL care medicine
*CRITICALLY ill
*BETA lactamases
*MICROBIAL enzymes
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Language
ISSN
0090-3493
Abstract
The article investigates the connection between antibiotic exposure and acquisition of antibiotic resistance in Pseudomonas (P.) aeruginosa and Enterobacter species among intensive care unit patients. It reveals that meropenem exposure produces the highest risk of developing resistance to P. aeruginosa. It also shows that increasing carbapenem use to address the emergence of Gram-negative bacteria producing extended-spectrum beta-lactamases results in antibiotic resistance in P. aeruginosa.