학술논문
Comparative outcomes after early Sotrovimab administration in vaccinated and unvaccinated kidney transplant recipients with SARS‐CoV‐2 infection during the Delta and Omicron BA.1 surges.
Document Type
Article
Author
Source
Subject
*SARS-CoV-2 Omicron variant
*KIDNEY transplantation
*SARS-CoV-2
*VACCINATION
*VACCINATION status
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Language
ISSN
1398-2273
Abstract
Abbreviations 95% CI 95% confidence interval AKI acute kidney injury eGFR estimated glomerular filtration rate ICU intensive care unit KTR kidney transplant recipients OR odds ratio SpAb spike antibody SuppO2 supplemental oxygen Organ transplant recipients respond suboptimally to SARS-CoV-2 vaccination and remain at risk for severe COVID-19 infections. Interval to Sotrovimab >=4 days from symptom onset was associated with an OR of 7.5 (95% CI: [1.56-36.17], I p i =.012) for requiring SuppO2: 55.6% required SuppO2 if interval to Sotrovimab was >=4 (versus 14.3% if <4 days). Demographics, characteristics at time of COVID-19 infection, COVID-19-related parameters, and outcomes, stratified by period of infection, are shown. [Extracted from the article]