학술논문

The time course of semantic activation in Parkinson's disease.
Document Type
Article
Source
Brain & Language. Oct2004, Vol. 91 Issue 1, p145-146. 21p. 1 Chart.
Subject
*PARKINSON'S disease
*EXTRAPYRAMIDAL disorders
*BRAIN diseases
*SEMANTICS
*LANGUAGE & languages
Language
ISSN
0093-934X
Abstract
This article presents a study, which aims to investigate the time course of spreading activation in Parkinson's disease (PD) using a list priming paradigm and multiple inter-stimulus intervals. It is predicted that a delayed time course of semantic activation will be evident in PD, such that semantic priming effects will only be expected at the longer inter-stimulus intervals (ISI) for PD participants. Analysis of the PD group's data revealed significant priming effects at the 1000 and 1500 ms ISI, however, no priming effects were evident at the 500 ms ISI. In contrast, analysis of the control group's data revealed significant priming effects at the 500, 1000, and 1500 ms ISI. Thus, the results the present study provide further support for both a delayed time course of semantic activation in PD and the influence of the striatum on information processing speed.