학술논문
Immunomodulation in human and experimental arthritis: including vitamin D, helminths and heat-shock proteins.
Document Type
Article
Author
Source
Subject
*IMMUNOREGULATION
*ARTHRITIS
*VITAMIN D
*HELMINTHS
*HEAT shock proteins
*
*
*
*
Language
ISSN
0961-2033
Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that is mainly directed to the joints, affecting the synovial membrane, the cartilage and also the bone. This disease affects 1% to 2% of the world population and is associated with significant morbidity and increased mortality. RA experimental models have allowed a great deal of information to be translated to the corresponding human disease. This review summarizes some of the most relevant findings targeting immunomodulation in arthritis. Some general guidelines to choose an adequate experimental model and also our experience with arthritis are supplied. [ABSTRACT FROM PUBLISHER]