학술논문

Regulation of tumor immune suppression and cancer cell survival by CXCL1/2 elevation in glioblastoma multiforme.
Document Type
Article
Source
Science Advances. 1/27/2021, Vol. 7 Issue 5, p1-12. 12p.
Subject
*GLIOBLASTOMA multiforme
*IMMUNOSUPPRESSION
*RECEPTOR for advanced glycation end products (RAGE)
*CANCER cells
*MEDICAL libraries
*PROGNOSIS
Language
ISSN
2375-2548
Abstract
The article discusses glioblastoma multiforme (GBM) has the common and fatal brain malignancy, with a poor 5-year survival rate of less than 5%. Topics include the invasiveness and high immune suppression of glioblastoma multiforme (GBM) produce poor survival of afflicted patients; and the combination of targeting CXCL1/2 and standard temozolomide chemotherapy improved upon the antitumor efficacy of chemotherapy.