부산대학교 도서관

Objectives: To compare the clinical, radiographic, and immunological outcomes between one‐piece versus two‐piece zirconia abutments supported single implant crowns in the esthetic region. Materials and Methods: The study followed a split‐mouth, double‐blind, and randomized controlled clinical design for a duration of 3 years. Twenty‐two eligible patients with 44 implants were randomly assigned to two groups: Group 1 (one‐piece zirconia abutment with zirconia base, n = 22) and Group 2 (two‐piece zirconia abutment with titanium base, n = 22). The primary outcome was the technical complication rate. Additionally, survival rates, cytokines concentrations in peri‐implant crevicular fluid (PICF), peri‐implant conditions, marginal bone loss, and pink/white esthetics score (PES/WES) were assessed as secondary outcomes. Results: Twelve of 22 patients attended the 1‐year follow‐up (due to the COVID pandemic), and 19 patients attended the 3‐year examination. Two abutments in Group 1 were fractured after 10 and 12 months in function. Additionally, one screw loosening occurred in Group 1 at 1‐year follow‐up. The 3‐year technical complication rate was significantly higher in Group 1 than that in Group 2 (15.79% vs. 0%, p <.001). The 3‐year implant survival rate was 100% in both groups. The concentration of IFN‐γ in PICF was significantly upregulated in Group 2 (p =.018). Furthermore, the IL‐6 concentration was positively correlated with BOP% (p =.020). Conclusions: Two‐piece zirconia abutments exhibited superior technical performance compared to one‐piece designs during a 3‐year follow‐up in the anterior region. However, further long‐term research is necessary to verify the immunological stability of two‐piece zirconia abutments. [ABSTRACT FROM AUTHOR]