부산대학교 도서관

Patients who had a previous history of malignant disease, patients with unclear records or patients with tumour-positive resection margins (R1) in the final histological report were excluded. In this case series, patients with PCF after primary laryngopharyngectomy started PORT significantly later than patients without PCF. Our literature search has resulted in only 1 single case series describing 9 patients with orocutaneous fistula and 8 patients with pharyngocutaneous fistula that received radiotherapy over an open fistula.[6] Though 10 of the 17 patients experienced a transient enlargement of the fistula during therapy, none of the patients suffered from any acute fistula-related secondary complication. The two patients irradiated despite open fistula in this series were treated by different physicians in 1994 (patient 2, table) and 2004 (patient 1, table), respectively. [Extracted from the article]