학술논문
p53: A tale of complexity and context.
Document Type
Article
Author
Source
Subject
*P53 protein
*PROTEINS
*
Language
ISSN
0092-8674
Abstract
The story of p53 is illuminating. Despite widespread attention, the tumor-suppressive functions of wild-type p53 or the oncogenic activities of its cancer-associated mutants are still not fully understood, and our discoveries have not yet led to major therapeutic breakthroughs. There is still much to learn about this fascinating protein. The story of p53 is illuminating. Despite widespread attention, the tumor-suppressive functions of wild-type p53 or the oncogenic activities of its cancer-associated mutants are still not, and our discoveries have not yet led to major therapeutic breakthroughs. There is still much to learn about this fascinating protein. [ABSTRACT FROM AUTHOR]