학술논문
Integrated 18 F‑fluorodeoxyglucose positron emission tomography magnetic resonance imaging (18 F‑FDGPET/MRI), a multimodality approach for comprehensive evaluation of dementia patients: A pictorial essay.
Document Type
Article
Source
Subject
*HIV infection complications
*ALZHEIMER'S disease
*BRAIN injuries
*COMBINED modality therapy
*CREUTZFELDT-Jakob disease
*DEMENTIA
*DEOXY sugars
*NEURODEGENERATION
*RADIOPHARMACEUTICALS
*POSITRON emission tomography
*VASCULAR dementia
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Language
ISSN
0971-3026
Abstract
Dementia, caused by irreversible neurodegenerative disorders such as Alzheimer's disease or reversible non‑degenerative conditions, is rapidly becoming one of the most alarming health problems in our aging society. This cognitive disorder associated with a multitude of clinical differentials with overlapping clinical, pathological, and imaging features is difficult to diagnose and treat, as it often presents late after significant neuronal damage has already occurred. Novel disease‑modifying treatments being developed will have to be corroborated with innovative imaging biomarkers so that earlier reliable diagnosis can be made and treatment initiated upon. Along with new specific PET radiotracers, integrated PET/MRI with combined methodological advantage and simultaneously acquired structural‑cum‑functional information may help achieve this goal. The present pictorial essay details our experiences with PET/MRI in dementing disorders, along with reviewing recent advances and future scope. [ABSTRACT FROM AUTHOR]