학술논문
An isogenic panel of App knock-in mouse models: Profiling β-secretase inhibition and endosomal abnormalities.
Document Type
Article
Author
Source
Subject
*AMYLOID plaque
*PRESENILINS
*AMYLOID beta-protein precursor
*LABORATORY mice
*ANIMAL disease models
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Language
ISSN
2375-2548
Abstract
The article presents a study which explores the isogenic panel of App knock-in mouse models, profiling beta secretase inhibition and endosomal abnormalities. It mentions that experimental comparisons between different isogenic App, knockin mouse lines will provide previously unidentified insights into the understanding of the etiology of Alzheimer's disease.