학술논문
Sodium retention by uPA‐plasmin‐ENaC in nephrotic syndrome—Authors reply.
Document Type
Article
Author
Source
Subject
*NEPHROTIC syndrome
*PLASMINOGEN activators
*SERINE proteinases
*BRUGADA syndrome
*SERUM albumin
*
*
*
*
Language
ISSN
1748-1708
Abstract
Sodium retention by uPA-plasmin-ENaC in nephrotic syndrome - Authors reply There is a great interest in exploring the mechanisms of oedema in nephrotic syndrome (NS) as evidenced by two parallel studies published in Acta Physiologica.[[1]] This has generated an editorial comment[3] which we respond to by this rebuttal. This seminal observation indicates that serine protease activity contributes to nephrotic sodium retention in mouse NS [8]; however, the importance of the individual protease(s) remains to be clarified. [Extracted from the article]