학술논문
Non-Gaussian diffusion MRI of gray matter is associated with cognitive impairment in multiple sclerosis.
Document Type
Article
Author
Source
Subject
*GAUSSIAN beams
*MAGNETIC resonance imaging
*GRAY matter (Nerve tissue)
*COGNITION disorders
*MULTIPLE sclerosis
*BIOMARKERS
*HISTOGRAMS
*RANK correlation (Statistics)
*PATIENTS
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Language
ISSN
1352-4585
Abstract
The article presents a study which examines the association of non-Gaussian diffusion magnetic resonance imaging (MRI) of gray matter (GM) with cognitive deficits in patients with multiple sclerosis (MS). The study is investigated by histogram analysis, Spearman rank correlations, and MRI. Results show that mean kurtosis (MK) was associated with cognitive impairment in MS patients and diffusional kurtosis imaging (DKI) can be use as biomarker for cortical injury.