학술논문

Fatal invasive candidiasis in COVID-19 patient with severe bleeding and extensively drug-resistant Klebsiella enterobacter.
Document Type
Article
Source
Journal of Infection in Developing Countries. Jun2022, Vol. 16 Issue 6, p1025-1029. 5p.
Subject
*COVID-19
*OPPORTUNISTIC infections
*INVASIVE candidiasis
*MYCOSES
*ENTEROBACTER
*KLEBSIELLA
Language
ISSN
2036-6590
Abstract
Introduction: Multi-organ dysfunction caused by thromboembolic complications may complicate the course of SARS-CoV-2 infection. Most patients require anticoagulant therapy which predisposes them to the development of hemorrhagic syndrome. In critically ill COVID-19 patients secondary infections due to opportunistic pathogens are associated with a high mortality rate. Case report: Herein, we present a COVID-19 patient with severe hemorrhage at unusual sites complicated with invasive candidiasis and an extensively drug-resistant (XDR) strain of Klebsiella enterobacter. Conclusions: Clinicians should be aware of the possibility for invasive fungal infections in severely ill patients with SARS-CoV-2 infection due to pre-existing conditions, risk factors, and COVID-19 associated pathological mechanisms. Management of invasive candidiasis is challenging because of the high prevalence of comorbidities, risk of toxicities, and drug interactions. [ABSTRACT FROM AUTHOR]