학술논문
Retinoblastoma protein represses transcription by recruiting a histone deacetylase.
Document Type
Article
Author
Source
Subject
*HISTONES
*RETINOBLASTOMA
*PROTEINS
*
*
Language
ISSN
0028-0836
Abstract
Reports that the histone deacetylase HDACI physically interacts and cooperates with retinoblastoma protein (Rb). The suggestion that the Rb/HDACI complex is a key element in the control of cell proliferation and differentiation and that it is a likely target for transforming viruses; How the retinoblastoma tumor-suppressor protein Rb inhibits cell proliferation; Methods.