학술논문
Evaluation of the Binax NOW Flu A+B Enzyme Immunochromatographic Assay in comparison with Real-Time PCR during the Pandemic of Influenza 2009.
Document Type
Article
Author
Source
Subject
*H1N1 influenza
*COMMUNICABLE disease diagnosis
*NEURAMINIDASE
*CHROMATOGRAPHIC analysis
*ENZYME-linked immunosorbent assay
*POLYMERASE chain reaction
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Language
ISSN
2218-2020
Abstract
The Binax NOW Flu A+B enzyme immunochromatographic assay was compared to Real-Time PCR assay for 542 specimen from nasal-wash or nasopharyngeal swab collected during the pandemic of 2009. The overall sensitivity, specificity, positive predictive value, and negative predictive value of the assay were 44.6%, 95.8%, 73.5%, and 86.9%, respectively. The assay sensitivity shows mixed values decreasing significantly in infants and children age, which is linked with the quality and the way sample is collected. [ABSTRACT FROM AUTHOR]