학술논문

High cell density and high-resolution 3D bioprinting for fabricating vascularized tissues.
Document Type
Article
Source
Science Advances. 2/22/2023, Vol. 9 Issue 8, p1-13. 13p.
Subject
*BIOPRINTING
*FUSED deposition modeling
*TISSUES
*ARTIFICIAL organs
*DENSITY
*B cells
Language
ISSN
2375-2548
Abstract
The article presents research on mitigating the scattering-induced deterioration of bioprinting resolution. The inclusion of iodixanol in the bioink enables a 10-fold reduction in light scattering and a substantial improvement in fabrication resolution for bioinks with a high cell density which were fabricated with fine vascular networks. The tissues were viable in a perfusion culture system, with endothelialization and angiogenesis observed after 14 days of culture.