학술논문
The Influence of Sedentary Behavior on the Relationship Between Cognitive Function and Vascular Function in Older Adults with and without Chronic Kidney Disease.
Document Type
Article
Author
Hannan, Mary (NURSE); Collins, Eileen G. (NURSE); Phillips, Shane A.; Quinn, Lauretta (NURSE); Steffen, Alana; Bronas, Ulf G.
Source
Subject
*COGNITION disorder risk factors
*ENDOTHELIUM physiology
*SEDENTARY lifestyles
*CHRONIC kidney failure
*CAROTID artery
*RESEARCH
*CARDIOVASCULAR system physiology
*BRACHIAL artery
*AGE distribution
*CONTINUING education units
*REGRESSION analysis
*ACTIGRAPHY
*RISK assessment
*ARTERIAL diseases
*NEUROPSYCHOLOGICAL tests
*RESEARCH funding
*FACTOR analysis
*BLOOD circulation
*DESCRIPTIVE statistics
*VASCULAR diseases
*COGNITIVE testing
*DATA analysis software
*SMOKING
*EDUCATIONAL attainment
*DISEASE risk factors
*MIDDLE age
*OLD age
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Language
ISSN
1526-744X
Abstract
Cognitive impairment and vascular dysfunction are common in older adults with and without chronic kidney disease (CKD). Older adults with and without CKD are also sedentary -- a behavior associated with cognitive and vascular function. The objective of this study was to explore whether sedentary behavior influenced the relationship between cognitive and vascular function in older adults with preclinical cognitive impairment with and without CKD. In our study, 48 older adults underwent assessment of cognition, vascular compliance, and sedentary behavior, and relationships were explored with regression moderation analysis. Sedentary time and breaks did not moderate the relationship between vascular and cognitive function. Although significant moderation was not found, cognition, vascular function, and sedentary behavior are important to assess when evaluating older adults with and without CKD. [ABSTRACT FROM AUTHOR]