학술논문

Hypercholesterolemia in Cancer and in Anorexia Nervosa: A Hypothesis for a Crosstalk.
Document Type
Article
Source
International Journal of Molecular Sciences. Jul2022, Vol. 23 Issue 13, p7466-N.PAG. 10p.
Subject
*ANOREXIA nervosa
*BLOOD cholesterol
*HYPERCHOLESTEREMIA
*EATING disorders
CANCER susceptibility
Language
ISSN
1661-6596
Abstract
The relationship between cholesterol and cancer has been widely demonstrated. Clinical studies have shown changes in blood cholesterol levels in cancer patients. In parallel, basic research studies have shown that cholesterol is involved in the mechanisms of onset and progression of the disease. On the other hand, anorexic patients have high cholesterol levels and a high susceptibility to cancer. In this review, we first present a brief background on the relations among nutrition, eating disorders and cancer. Using several notable examples, we then illustrate the changes in cholesterol in cancer and in anorexia nervosa, providing evidence for their important relationship. Finally, we show a new possible link between cholesterol disorder in cancer and in anorexia nervosa. [ABSTRACT FROM AUTHOR]