학술논문

Nonsebaceous lymphadenoma arising as a painless subcutaneous nodule on the eyebrow.
Document Type
Article
Source
Journal of Cutaneous Pathology. Nov2022, Vol. 49 Issue 11, p934-937. 4p. 4 Color Photographs, 1 Chart.
Subject
*HODGKIN'S disease
*SALIVARY glands
*EYEBROWS
*GERMINAL centers
*DIFFERENTIAL diagnosis
Language
ISSN
0303-6987
Abstract
Salivary gland tumors can rarely present in skin excision specimens and can pose a diagnostic challenge to dermatopathologists. We present an exceptional case of a salivary gland type nonsebaceous lymphadenoma presenting as a painless subcutaneous nodule on the right medial eyebrow of a 16‐year‐old male, mimicking a primary cutaneous adnexal neoplasm. Histologic evaluation revealed a well‐circumscribed to partially encapsulated nodule with a marked lymphoid infiltrate including reactive germinal centers. Within the lymphoid component was a central epithelial cystic neoplasm with tubuloglandular and basaloid differentiation. There was no myoepithelial component to suggest a chondroid syringoma. No sebaceous differentiation was present. The overall histopathological and immunohistochemical findings were consistent with a nonsebaceous lymphadenoma. Dermatopathologists should consider salivary gland type lymphadenoma as a differential diagnosis when encountering a subcutaneous lesion with lymphoid, cystic, glandular, and basaloid components. [ABSTRACT FROM AUTHOR]