학술논문

Measles outbreak in Tanzania, 2006–2007
Document Type
Article
Source
Vaccine. Aug2010, Vol. 28 Issue 37, p5979-5985. 7p.
Subject
*MEASLES vaccines
*VACCINATION
*DISEASE outbreaks
*IMMUNIZATION
*DRUG dosage
*DRUG efficacy
*AGE distribution
*PUBLIC health surveillance
Language
ISSN
0264-410X
Abstract
Abstract: We conducted a measles outbreak investigation in Dar es Salaam, Tanzania. Surveillance data were analyzed; a susceptibility profile developed, and case–control study conducted. The age distribution of cases peaked among those <2, 5–7, and ≥18 years, corresponding to the age distribution of susceptibles. Risk factors included being unvaccinated (aOR=5.7, p <0.01) or having received one dose of vaccine compared to two (aOR=2.4, p =0.01), being younger, and having a less-educated caretaker. Vaccine effectiveness was 88% (one dose) and 96% (two doses). Results highlight the importance of receiving one dose of measles vaccine, and the added benefit of two doses. [ABSTRACT FROM AUTHOR]