학술논문

Checkpoint inhibitors and anti-angiogenic agents: a winning combination.
Document Type
Article
Source
British Journal of Cancer. Oct2023, Vol. 129 Issue 9, p1367-1372. 6p.
Subject
Language
ISSN
0007-0920
Abstract
The combination of immune checkpoint inhibitors and anti-angiogenic agents is a promising new approach in cancer treatment. Immune checkpoint inhibitors block the signals that help cancer cells evade the immune system, while anti-angiogenic agents target the blood vessels that supply the tumour with nutrients and oxygen, limiting its growth. Importantly, this combination triggers synergistic effects based on molecular and cellular mechanisms, leading to better response rates and longer progression-free survival than treatment alone. However, these combinations can also lead to increased side effects and require close monitoring. [ABSTRACT FROM AUTHOR]