학술논문
Design, data monitoring, and analysis of clinical trials with co-primary endpoints: A review.
Document Type
Article
Source
Subject
*CLINICAL trials
*MEDICAL research
*GROUP sequential design
*DATA analysis
*CODING theory
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Language
ISSN
1054-3406
Abstract
We review the design, data monitoring, and analyses of clinical trials with co-primary endpoints. Recently developed methods for fixed-sample and group-sequential settings are described. Practical considerations are discussed, and guidance for the application of these methods is provided. [ABSTRACT FROM PUBLISHER]