소장자료
LDR | 02287nam a22003378a 4500 | ||
001 | 0091895270▲ | ||
003 | Uk▲ | ||
005 | 20180520064802▲ | ||
008 | 101201s2011 nyua 001 0 eng|d▲ | ||
015 | ▼aGBB0E5917▼2bnb▲ | ||
020 | ▼a9781441984166 (hbk.) :▼c?11.50▲ | ||
020 | ▼a144198416X (hbk.) :▼c?11.50▲ | ||
040 | ▼aStDuBDS▼beng▼cStDuBDS▲ | ||
082 | 0 | 4 | ▼a616.994061▼221▲ |
090 | ▼a616.994061▼bT185j▲ | ||
245 | 0 | 0 | ▼aTargeted drug strategies for cancer and inflammation /▼cedited by Ann L. Jackman, Christopher P. Leamon.▲ |
260 | ▼aNew York ;▼aLondon :▼bSpringer,▼c2011.▲ | ||
263 | ▼a201103▲ | ||
300 | ▼axi, 221 p. :▼bill. ;▼c24 cm.▲ | ||
500 | ▼aIncludes index.▲ | ||
505 | 0 | ▼aBiological Role, Properties and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1).- Folate Receptors and Therapeutic Applications.- Hormonal Control of Folate Receptor Genes.- Folate Receptor Targeted Radionuclide Imaging Agents.- Folate receptor targeted thymidylate synthase inhibitors.- Discovery of novel antifolate inhibitors of de novo purine nucleotide biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry.- Folate-receptor targeted cancer chemotherapy.- Anti-FR antibody generation and engineering: development of new therapeutic tools.- Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases.- Targeting Activated Macrophages via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders.-▲ | |
520 | ▼aThis book describes progress in the use of folates to transport antifolate drugs such as raltitrexed and pemetrexed that block the mechanisms of cancer. Covers development of FR-targeted antifolate drugs and folate conjugates bearing a range of payloads (including cytotoxic drugs).▲ | ||
650 | 0 | ▼aFolic acid▼xTherapeutic use.▲ | |
650 | 0 | ▼aDrug carriers (Pharmacy)▲ | |
650 | 0 | ▼aAntineoplastic agents▼xTherapeutic use.▲ | |
650 | 0 | ▼aCancer▼xChemotherapy.▲ | |
650 | 0 | ▼aInflammation▼xChemotherapy.▲ | |
650 | 0 | ▼aDiagnostic imaging.▲ | |
700 | 1 | ▼aJackman, Ann L.▲ | |
700 | 1 | ▼aLeamon, Christopher P.▲ | |
999 | ▼c정영주▲ |
Targeted drug strategies for cancer and inflammation
자료유형
국외단행본
서명/책임사항
Targeted drug strategies for cancer and inflammation / edited by Ann L. Jackman, Christopher P. Leamon.
발행사항
New York ; London : Springer , 2011.
형태사항
xi, 221 p. : ill. ; 24 cm.
일반주기
Includes index.
내용주기
Biological Role, Properties and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1).- Folate Receptors and Therapeutic Applications.- Hormonal Control of Folate Receptor Genes.- Folate Receptor Targeted Radionuclide Imaging Agents.- Folate receptor targeted thymidylate synthase inhibitors.- Discovery of novel antifolate inhibitors of de novo purine nucleotide biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry.- Folate-receptor targeted cancer chemotherapy.- Anti-FR antibody generation and engineering: development of new therapeutic tools.- Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases.- Targeting Activated Macrophages via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders.-
요약주기
This book describes progress in the use of folates to transport antifolate drugs such as raltitrexed and pemetrexed that block the mechanisms of cancer. Covers development of FR-targeted antifolate drugs and folate conjugates bearing a range of payloads (including cytotoxic drugs).
주제
ISBN
9781441984166 (hbk.) 144198416X (hbk.)
청구기호
616.994061 T185j
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