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Vaccinating Ohio Adults With Intellectual and Developmental Disabilities Against COVID-19 [electronic resource].

The Ohio State University. Psychology.

[S.l.] : The Ohio State University. 2024 Ann Arbor : ProQuest Dissertations & Theses , 2024

1 online resource(163 p.)

Source: Dissertations Abstracts International, Volume: 86-04, Section: B.
Advisor: Havercamp, Susan M.

Thesis (Ph.D.)--The Ohio State University, 2024.

Individuals with intellectual and developmental disabilities (IDD) experienced poor health outcomes and significant health disparities before the onset of the COVID-19 pandemic. Multiple studies have shown that people with IDD were at higher risk of contracting COVID-19 and that they experienced higher mortality rates than the general population. Little is currently known about the vaccination of Americans with IDD against COVID-19. Using the Epic Cosmos Dataset, we analyzed deidentified electronic health record data from n=6,964,806 adult Ohioans to perform a retroactive cohort study comparing infections, illness severity, vaccination rates, and vaccine effectiveness between adult Ohioans with (n=52,896) and without IDD (n=6,911,910). Logistic regression analyses were used to examine and compare vaccination, infection, and illness severity. We examined how vaccination and infection rates differed by clinically relevant variables including demographics, IDD diagnoses, and factors known to increase risk for adverse COVID-19 outcomes (e.g., smoking, asthma, cancer). We found that adult Ohioans with IDD had higher vaccination and infection rates than those without IDD. Indicators of vaccine effectiveness were superior in those with IDD for preventing infections, as well as severe illness or death. Vaccinations over time suggest that adults with IDD utilized the early vaccine prioritization period afforded to them in Ohio. Results support the assertation that vulnerable populations, including those with IDD, should be prioritized for early vaccine access planning during future public health emergencies.

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