학술논문

Novel Insights in Fetal Cardiomyopathy due to in utero Herpes Simplex Virus Infection
Document Type
Academic Journal
Source
Fetal Diagnosis and Therapy. October, 2017, Vol. 42 Issue 3, p236, 4 p.
Subject
Virus diseases
Herpes simplex virus
Pregnant women
Myocardial diseases
Disease transmission
Herpes simplex
Death
Skin
Fetal death
Necrosis
Liver
Recurrence (Disease)
Herpesvirus infections
Language
English
ISSN
1015-3837
Abstract
This is a case report of fatal cardiomyopathy in a fetus following maternal intrauterine infection with herpes simplex virus (HSV), despite the mother having no symptoms of an infection. The fetus showed signs of a disseminated infection affecting the heart, brain, lungs, liver, adrenal glands, and skin. HSV cardiomyopathy, characterized by vast necrosis, extensive calcifications, and inflammatory infiltration, was found to be the cause of intrauterine fetal death. To our knowledge, this is a unique report of an asymptomatic maternal nonprimary or recurrent HSV infection that induced a transmission of HSV resulting in extensive and fatal changes in the fetal heart. Keywords Sonography * Herpes simplex virus * Fetal cardiomyopathy * Prenatal diagnosis
Case Report A 24-year-old gravida 4 para 1 patient presented with vaginal bleeding and preterm labor at 26+3 weeks of gestation. In 2007, she had given birth to a healthy [...]