학술논문
Transplantation for accidental acute high-dose total body neutron- and [gamma]-radiation exposure
Document Type
Academic Journal
Author
Source
Bone Marrow Transplantation. June, 2002, Vol. 29 Issue 11, p935
Subject
Language
English
ISSN
0268-3369
Abstract
Accidental exposure to acute high-dose total body neutron radiation is rare. We report a 35-year-old man exposed to a total body dose of 5.4 Gy neutron- and 8.5-13 Gy [gamma]-radiation in a radiation criticality accident. He received a blood stem cell transplant from his HLA-identical sister. There was bone marrow recovery with complete donor chimerism. Random chromatid breaks were observed in donor cells suggesting a bystander effect of neutron exposure. The subject died 82 days after the accident (75 days post transplant) from multi-organ failure. Bone Marrow Transplantation(2002) 29:, 935-939. DOI:10.1038/sj/bmt/1703568 Keywords: transplantation, radiation, neutron, [gamma]-ray, bystander effect
Author(s): S Chiba [1]; A Saito [1]; S Ogawa [2]; K Takeuchi [3]; K Kumano [1]; S Seo [2]; T Suzuki [2]; Y Tanaka [2]; T Saito [2]; K Izutsu [...]
Author(s): S Chiba [1]; A Saito [1]; S Ogawa [2]; K Takeuchi [3]; K Kumano [1]; S Seo [2]; T Suzuki [2]; Y Tanaka [2]; T Saito [2]; K Izutsu [...]